Ludmer Centre for Neuroinformatics and Mental Health

McGill Centre for Integrative Neuroscience

Samir Das
Director of Technology

Montreal Neurological Institute

WHAT IS LORIS?

“..is a modular and extensible web-based data and project management software that integrates all aspects of a multi-center neuroimaging research study. It is an OPEN SOURCE framework and database suitable for managing large datasets.”

Extensible and modular design

LORIS Globally

WHAT IS CBRAIN?


“..is an OPEN SOURCE web-based collaborative High-Performance Computing (HPC) platform for neuroimaging research, connecting researchers to the tools required to handle large datasets.”

What does CBRAIN do?

..enables distributed execution of software pipelines

..aggregates multiple distributed file systems into uniform view

LORIS-CBRAIN INTEGRATION

NIAK

http://niak.simexp-lab.org/

BrainBrowser

..a set of web-based 3D visualization tools primarily used for viewing neurological data i.e. MRI scans.

It allows for real-time manipulation and analysis of 3D neuroimaging data through any modern web browser. TRY ME!

BigBrain

The BigBrain is the digitized reconstruction of 7404 hi-res coronal histological sections (20 microns isotropic).

It is the brain of a 65 year-old man with no neurological or psychiatric diseases in clinical records at time of death.

BigBrain - high resolution reference brain

Multimodal integration into an anatomically realistic standard space

Years of development

20 micron resolution

7404 histological slices

1 Terabyte dataset

Click to launch the Neuroglancer Viewer!

  • 8 year study
  • Longitudinal data
  • 532 subjects
  • 8000 distinct variables
  • 37000 individual assessments
  • T1, T2, PD, DTI
  • Spectroscopy
  • ∼3TB of imaging data
  • 2000 MRI acquisitions

  • Infant brain development in autism
  • 3000+ scans
  • 700+ subjects
  • 7000 distinct variables
  • 150,000+ individual assessments
  • T1, T2, DTI, BOLD
  • ∼5 TBs of imaging data
  • Genetic/biospecimen data

Open Science

Thank you!Acknowledgements: Alan Evans, Alex Zijdenbos, Dario Vins, Jonathan Harlap, Matt Charlet, Andrew Corderey, Sebastian Muehlboeck, Reza Adalat, Louis Collins, Vladimir Fonov, Marc Rousseau, Mia Petkova, Rathi Gnanasekaran, David Brownlee, Tarek Sherif, Pierre Rioux, Nic Kassis, Leigh MacIntyre, Claude Lepage, Ilana Leppert, Natasha Beck, Tristan Glatard, Bert Vincent, Lindsay Lewis, Najma Mahani, Elodie Portales-Casamar, Alden Woodward, Sylvain Milot, Jean Francois Malouin, Sylvain Baillet, Daniel Kroetz, Martin Weiss, Mathieu Desrosier, Jason Karamchandani, Amit Bar-Or, Ted Fon, John Brietner, Derek Lo, Patrick Bermudez, Chris Steele, Pamela Patterson and one of my favourites: Pierre Bellec!

LORIS team on left